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Human Affinity® Story
What is "Bioactive"?
In medical dictionaries, a bioactive substance is defined as a substance having an effect on, causes a reaction, or triggers a response in the living tissue1
There are different bioactive ingredients in lactating secretion, including human milk oligosaccharides (HMO) and immunoglobulin2.
HMO
HMO is third key nutrients in lactating secretion
MOS
MOS contains innate levels of sialyllactose
Bioactive Affinity Ingredients – 2 types of HMO & MOS*
Clinically proven to support immunity in 3 ways
BLOCK 
GUT BARRIER
A healthy gut barrier helps to block pathogens from entering the body4.
Unhealthy gut barrier |
Healthy gut barrier |
 PathogensMOS contributes to a healthy gut barrier5. |
|
MODULATE GUT MICROBIOTA
Increasing beneficial bacteria in the gut microbiota supports gut health6.
Group that doesn’t consume formula containing 2 types of HMO and MOS |
Group that consumes formula containing 2 types of HMO and MOS |
Pathogens  Beneficial bacteria in the gutHMO and MOS promote a microbiota similar to breastfed infants7,8. |
|
DEVELOP IMMUNE FUNCTION
The bioactive antibody (sIgA) plays a key role in gastrointestinal immune function9.
Group that doesn’t consume formula containing MOS |
Group that consumes formula containing MOS |
| HMO and MOS help foster immune functions. In fecal samples, the level of the bioactive antibody, sIgA, was found to be doubled in babies taking products containing MOS2,5. |
|
*2 types of HMO refers to 2’-Fucosyllactose(2’-FL) and Lacto-N-neotetraose (LNnT); MOS refers to Milk oligosaccharides
Revolutionary Bioactive ingredient MOS*
Babies consuming milk formula with MOS7:
2 types of HMO*
Babies consuming formula with 2 types of HMO (2’-FL and LNnT) were found to have a reduced reporting of the below issues10:
*2 types of HMO refers to 2’-Fucosyllactose (2’-FL) and Lacto-N-neotetraose (LNnT); MOS refers to Milk oligosaccharides
^Compared with control group
References:
1. Guaddaoui A et al. Int J Nutr Food Sci. 2014;3(3):174-179.
2. Ballard O, Morrow AL. Pediatr Clin North Am. 2013;60(1):49-74.
3. Urashima T et al. Adv Nutr. 2012;3:473S-482S.
4. Anderson RC et al. Colitis. 2012. DOI: 10.5772/25753.
5. Estorninos E et al. Abstract presented at the FASEB Science Research Conferences Nutritional Immunology and the Microbiota: Rules of Engagement in Health and Disease. 24-29 June 2018, Virginia, USA.
6. O’Neill I et al. Emerg Top Life Sci (2017) 1 (4): 333–349.
7. Estorninos E et al. JPGN. 2019;58(1):999.
8. Steenhout P et al. FASEBJ. 2016;30(Suppl 1):275-277.
9. Bakker-Zierikzee AM et al. Pediatr Allergy Immunol. 2006;17:134-140.
10. Puccios G et al. JPGN. 2017;64(4):624-631.
IMPORTANT ADVICE FOR MOTHERS
Breast-feeding
Breast milk is the best for babies and provides the best nutrition and protection from illness for your baby. For most infants, breast milk is all that is needed for the first 6 months. Many mothers continue to breast-feed after 6 months and then give other foods as well. For advice on breast-feeding, consult your doctor or any other health professional, or a friend or relative who has successfully breastfed. Frequent feeding is the best way to establish and maintain a good milk supply. A well balanced diet, both during pregnancy and after delivery, also helps sustain and adequate supply of breast milk.
Advice especially for the working mothers
Your baby can still receive the benefits of breast milk even if you go out to work. Partial breast-feeding is better that bottle-feeding completely, so continue to breast-feed even if you have been advised to give other foods. If you sleep with your baby, he will breast-feed during the night without disturbing you. Before you leave home in the morning and again when you return, breast-feed your baby. When mixed feeding, always offer the breast before giving other foods.
Remember: Breast milk is the best and most economical food for your baby.
Seek advice
The use of foods which are not intended for young babies can be harmful. Unnecessary introduction of partial bottle-feeding or other foods and drinks, will have a negative effect on breast-feeding. Therefore, always consult a health professional before introducing anything other than breast milk.
Using a breast milk substitute
If a doctor or other health professional recommends a supplement to breast-feeding, or its replacement, during the first 6 months, it is preferable to use an infant formula meeting recognized quality standards.
When used correctly this supplies the nutritional needs of your baby in an easily digestible form. You will need more than 450 g per week if your baby is only bottle-fed, so keep your family circumstances and costs in mind before deciding whether to use infant formula.
As soon as your baby is old enough, feed infant formula with a cup and spoon.